De novo gene evolution: How do we transition from non-coding to coding?

Created on 28th June 2017

Jorge Ruiz-Orera; José Luis Villanueva-Cañas; William Blevins; M.Mar Albà;

Recent years have witnessed the discovery of protein–coding genes which appear to have evolved de novo from previously non-coding sequences. This has changed the long-standing view that coding sequences can only evolve from other coding sequences. However, there are still many open questions regarding how new protein-coding sequences can arise from non-genic DNA.

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